Phase II Study of Iniparib with Concurrent Chemoradiation in Patients with Newly Diagnosed Glioblastoma

PURPOSE: Iniparib is a purported prodrug causing cell death through intracellular conversion to nitro radical ions. We assessed the efficacy and safety of iniparib with standard radiation therapy (RT) and temozolomide (TMZ) in patients with newly diagnosed glioblastoma (GBM). EXPERIMENTAL DESIGN: Ad...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Blakeley, Jaishri O., Grossman, Stuart A., Chi, Andrew S., Mikkelsen, Tom, Rosenfeld, Myrna R., Ahluwalia, Manmeet S., Nabors, L. Burt, Eichler, April, Ribas, Ignacio Garcia, Desideri, Serena, Ye, Xiaobu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367923/
https://ncbi.nlm.nih.gov/pubmed/30131387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0110
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