Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma

BACKGROUND: In this phase II trial, we investigated the efficacy of a metronomic temozolomide schedule in the treatment of recurrent malignant gliomas (MGs). METHODS: Eligible patients received daily temozolomide (50 mg/m(2)) continuously until progression. The primary endpoint was progression-free...

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Bibliografiske detaljer
Main Authors: Omuro, Antonio, Chan, Timothy A., Abrey, Lauren E., Khasraw, Mustafa, Reiner, Anne S., Kaley, Thomas J., DeAngelis, Lisa M., Lassman, Andrew B., Nolan, Craig P., Gavrilovic, Igor T., Hormigo, Adilia, Salvant, Cynthia, Heguy, Adriana, Kaufman, Andrew, Huse, Jason T., Panageas, Katherine S., Hottinger, Andreas F., Mellinghoff, Ingo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Clinical Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548585/
https://ncbi.nlm.nih.gov/pubmed/23243055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos295
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