Phase II study of monthly pasireotide LAR (SOM230C) for recurrent or progressive meningioma

OBJECTIVE: A subset of meningiomas recur after surgery and radiation therapy, but no medical therapy for recurrent meningioma has proven effective. METHODS: Pasireotide LAR is a long-acting somatostatin analog that may inhibit meningioma growth. This was a phase II trial in patients with histologica...

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Pubblicato in:Neurology
Autori principali: Norden, Andrew D., Ligon, Keith L., Hammond, Samantha N., Muzikansky, Alona, Reardon, David A., Kaley, Thomas J., Batchelor, Tracy T., Plotkin, Scott R., Raizer, Jeffrey J., Wong, Eric T., Drappatz, Jan, Lesser, Glenn J., Haidar, Sam, Beroukhim, Rameen, Lee, Eudocia Q., Doherty, Lisa, Lafrankie, Debra, Gaffey, Sarah C., Gerard, Mary, Smith, Katrina H., McCluskey, Christine, Phuphanich, Surasak, Wen, Patrick Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335993/
https://ncbi.nlm.nih.gov/pubmed/25527270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001153
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