Phase II study of monthly pasireotide LAR (SOM230C) for recurrent or progressive meningioma

OBJECTIVE: A subset of meningiomas recur after surgery and radiation therapy, but no medical therapy for recurrent meningioma has proven effective. METHODS: Pasireotide LAR is a long-acting somatostatin analog that may inhibit meningioma growth. This was a phase II trial in patients with histologica...

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Vydáno v:Neurology
Hlavní autoři: Norden, Andrew D., Ligon, Keith L., Hammond, Samantha N., Muzikansky, Alona, Reardon, David A., Kaley, Thomas J., Batchelor, Tracy T., Plotkin, Scott R., Raizer, Jeffrey J., Wong, Eric T., Drappatz, Jan, Lesser, Glenn J., Haidar, Sam, Beroukhim, Rameen, Lee, Eudocia Q., Doherty, Lisa, Lafrankie, Debra, Gaffey, Sarah C., Gerard, Mary, Smith, Katrina H., McCluskey, Christine, Phuphanich, Surasak, Wen, Patrick Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335993/
https://ncbi.nlm.nih.gov/pubmed/25527270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001153
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