Human lung stem cells: Oh, the places you'll go!

Por Königshoff, Melanie, Schwarz, Johannes, Eickelberg, Oliver
Publicado em 2011

Enolase 1 (ENO1) and protein disulfide-isomerase associated 3 (PDIA3) regulate Wnt/β-catenin-driven trans-differentiation of murine alveolar epithelial cells

Por Mutze, Kathrin, Vierkotten, Sarah, Milosevic, Jadranka, Eickelberg, Oliver, Königshoff, Melanie
Publicado no Dis Model Mech (2015)

Multidimensional immunolabeling and 4D time-lapse imaging of vital ex vivo lung tissue

Por Burgstaller, Gerald, Vierkotten, Sarah, Lindner, Michael, Königshoff, Melanie, Eickelberg, Oliver
Publicado no Am J Physiol Lung Cell Mol Physiol (2015)

Linking bronchopulmonary dysplasia to adult chronic lung diseases: role of WNT signaling

Por Ota, Chiharu, Baarsma, Hoeke A., Wagner, Darcy E., Hilgendorff, Anne, Königshoff, Melanie
Publicado no Mol Cell Pediatr (2016)

No involvement of alveolar macrophages in the initiation of carbon nanoparticle induced acute lung inflammation in mice

Por Chen, Shanze, Yin, Renfu, Mutze, Kathrin, Yu, Youjia, Takenaka, Shinji, Königshoff, Melanie, Stoeger, Tobias
Publicado no Part Fibre Toxicol (2016)

Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis

Por Königshoff, Melanie, Balsara, Nisha, Pfaff, Eva-Maria, Kramer, Monika, Chrobak, Izabella, Seeger, Werner, Eickelberg, Oliver
Publicado em 2008

Validation of the 2(nd) Generation Proteasome Inhibitor Oprozomib for Local Therapy of Pulmonary Fibrosis

Por Semren, Nora, Habel-Ungewitter, Nunja C., Fernandez, Isis E., Königshoff, Melanie, Eickelberg, Oliver, Stöger, Tobias, Meiners, Silke
Publicado no PLoS One (2015)

Coactivator-Associated Arginine Methyltransferase-1 Function in Alveolar Epithelial Senescence and Elastase-Induced Emphysema Susceptibility

Por Sarker, Rim S. J., John-Schuster, Gerrit, Bohla, Alexander, Mutze, Kathrin, Burgstaller, Gerald, Bedford, Mark T., Königshoff, Melanie, Eickelberg, Oliver, Yildirim, Ali Ö.
Publicado no Am J Respir Cell Mol Biol (2015)

S100a4 Is Secreted by Alternatively Activated Alveolar Macrophages and Promotes Activation of Lung Fibroblasts in Pulmonary Fibrosis

Por Zhang, Wei, Ohno, Shinji, Steer, Beatrix, Klee, Stephan, Staab-Weijnitz, Claudia A., Wagner, Darcy, Lehmann, Mareike, Stoeger, Tobias, Königshoff, Melanie, Adler, Heiko
Publicado no Front Immunol (2018)

SFTA2—A Novel Secretory Peptide Highly Expressed in the Lung—Is Modulated by Lipopolysaccharide but Not Hyperoxia

Por Mittal, Rashmi A., Hammel, Markus, Schwarz, Johannes, Heschl, Katharina M., Bretschneider, Nancy, Flemmer, Andreas W., Herber-Jonat, Susanne, Königshoff, Melanie, Eickelberg, Oliver, Holzinger, Andreas
Publicado em 2012

WNT1-inducible signaling protein–1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis

Por Königshoff, Melanie, Kramer, Monika, Balsara, Nisha, Wilhelm, Jochen, Amarie, Oana Veronica, Jahn, Andreas, Rose, Frank, Fink, Ludger, Seeger, Werner, Schaefer, Liliana, Günther, Andreas, Eickelberg, Oliver
Publicado em 2009

Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis

Por Nikolova, Sevdalina, Guenther, Andreas, Savai, Rajkumar, Weissmann, Norbert, Ghofrani, Hossein A, Konigshoff, Melanie, Eickelberg, Oliver, Klepetko, Walter, Voswinckel, Robert, Seeger, Werner, Grimminger, Friedrich, Schermuly, Ralph T, Pullamsetti, Soni S
Publicado em 2010

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo

Por Lehmann, Mareike, Korfei, Martina, Mutze, Kathrin, Klee, Stephan, Skronska-Wasek, Wioletta, Alsafadi, Hani N., Ota, Chiharu, Costa, Rita, Schiller, Herbert B., Lindner, Michael, Wagner, Darcy E., Günther, Andreas, Königshoff, Melanie
Publicado no Eur Respir J (2017)

Towards a global initiative for fibrosis treatment (GIFT)

Por Molina-Molina, Maria, Agusti, Alvar, Crestani, Bruno, Schwartz, David A., Königshoff, Melanie, Chambers, Rachel C., Maher, Toby M., Faner, Rosa, Mora, Ana Lucia, Rojas, Mauricio, Antoniou, Katerina M., Sellares, Jacobo
Publicado no ERJ Open Res (2017)

Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis

Por Zhou, Qiyuan, Pardo, Annie, Königshoff, Melanie, Eickelberg, Oliver, Budinger, G. R. Scott, Thavarajah, Krishna, Gottardi, Cara J., Jones, Jonathan, Varga, John, Selman, Moises, Sznajder, Jacob I., Raj, J. Usha, Zhou, Guofei
Publicado em 2011

BARD1 mediates TGF-β signaling in pulmonary fibrosis

Por André, Pierre-Alain, Prêle, Cecilia M., Vierkotten, Sarah, Carnesecchi, Stéphanie, Donati, Yves, Chambers, Rachel C., Pache, Jean-Claude, Crestani, Bruno, Barazzone-Argiroffo, Constance, Königshoff, Melanie, Laurent, Geoffrey J., Irminger-Finger, Irmgard
Publicado no Respir Res (2015)

Pulmonary Epithelium Is a Prominent Source of Proteinase-activated Receptor-1–inducible CCL2 in Pulmonary Fibrosis

Por Mercer, Paul F., Johns, Robin H., Scotton, Chris J., Krupiczojc, Malvina A., Königshoff, Melanie, Howell, David C. J., McAnulty, Robin J., Das, Anuk, Thorley, Andrew J., Tetley, Terry D., Eickelberg, Oliver, Chambers, Rachel C.
Publicado em 2009

Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis

Por Bardou, Olivier, Menou, Awen, François, Charlène, Duitman, Jan Willem, von der Thüsen, Jan H., Borie, Raphaël, Sales, Katiuchia Uzzun, Mutze, Kathrin, Castier, Yves, Sage, Edouard, Liu, Ligong, Bugge, Thomas H., Fairlie, David P., Königshoff, Mélanie, Crestani, Bruno, Borensztajn, Keren S.
Publicado no Am J Respir Crit Care Med (2016)

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

Por Baarsma, Hoeke A., Skronska-Wasek, Wioletta, Mutze, Kathrin, Ciolek, Florian, Wagner, Darcy E., John-Schuster, Gerrit, Heinzelmann, Katharina, Günther, Andreas, Bracke, Ken R., Dagouassat, Maylis, Boczkowski, Jorge, Brusselle, Guy G., Smits, Ron, Eickelberg, Oliver, Yildirim, Ali Ö., Königshoff, Melanie
Publicado no J Exp Med (2017)

Correction: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

Por Baarsma, Hoeke A., Skronska-Wasek, Wioletta, Mutze, Kathrin, Ciolek, Florian, Wagner, Darcy E., John-Schuster, Gerrit, Heinzelmann, Katharina, Günther, Andreas, Bracke, Ken R., Dagouassat, Maylis, Boczkowski, Jorge, Brusselle, Guy G., Smits, Ron, Eickelberg, Oliver, Yildirim, Ali Ö., Königshoff, Melanie
Publicado no J Exp Med (2017)