Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis

Rationale: Idiopathic pulmonary fibrosis (IPF) is a devastating disease that remains refractory to current therapies. Objectives: To characterize the expression and activity of the membrane-anchored serine protease matriptase in IPF in humans and unravel its potential role in human and experimental...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Bardou, Olivier, Menou, Awen, François, Charlène, Duitman, Jan Willem, von der Thüsen, Jan H., Borie, Raphaël, Sales, Katiuchia Uzzun, Mutze, Kathrin, Castier, Yves, Sage, Edouard, Liu, Ligong, Bugge, Thomas H., Fairlie, David P., Königshoff, Mélanie, Crestani, Bruno, Borensztajn, Keren S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849177/
https://ncbi.nlm.nih.gov/pubmed/26599507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201502-0299OC
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