The Protease Inhibitor HAI-2, but Not HAI-1, Regulates Matriptase Activation and Shedding through Prostasin

The membrane-anchored serine proteases, matriptase and prostasin, and the membrane-anchored serine protease inhibitors, hepatocyte growth factor activator inhibitor (HAI)-1 and HAI-2, are critical effectors of epithelial development and postnatal epithelial homeostasis. Matriptase and prostasin form...

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Autores principales: Friis, Stine, Sales, Katiuchia Uzzun, Schafer, Jeffrey Martin, Vogel, Lotte K., Kataoka, Hiroaki, Bugge, Thomas H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139241/
https://ncbi.nlm.nih.gov/pubmed/24962579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574400
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