S100a4 Is Secreted by Alternatively Activated Alveolar Macrophages and Promotes Activation of Lung Fibroblasts in Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease, characterized by damage of lung epithelial cells, excessive deposition of extracellular matrix in the lung interstitium, and enhanced activation and proliferation of fibroblasts. S100a4, also termed FSP-1 (fibroblast-spe...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhang, Wei, Ohno, Shinji, Steer, Beatrix, Klee, Stephan, Staab-Weijnitz, Claudia A., Wagner, Darcy, Lehmann, Mareike, Stoeger, Tobias, Königshoff, Melanie, Adler, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992816/
https://ncbi.nlm.nih.gov/pubmed/29910813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01216
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