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Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Repetitive injury and reprogramming of the lung epithelium are thought to be critical drivers of disease progression, contributing to fibroblast activation, extracellular matrix remodeling, and subsequently loss of...

詳細記述

保存先:
書誌詳細
出版年:Respir Res
主要な著者: Lehmann, Mareike, Buhl, Lara, Alsafadi, Hani N., Klee, Stephan, Hermann, Sarah, Mutze, Kathrin, Ota, Chiharu, Lindner, Michael, Behr, Jürgen, Hilgendorff, Anne, Wagner, Darcy E., Königshoff, Melanie
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138909/
https://ncbi.nlm.nih.gov/pubmed/30219058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0876-y
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