WNT1-inducible signaling protein–1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is characterized by distorted lung architecture and loss of respiratory function. Enhanced (myo)fibroblast activation, ECM deposition, and alveolar epithelial type II (ATII) cell dysfunction contribute to IPF pathogenesis. However, the molecular pathways linking A...

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Detalhes bibliográficos
Main Authors: Königshoff, Melanie, Kramer, Monika, Balsara, Nisha, Wilhelm, Jochen, Amarie, Oana Veronica, Jahn, Andreas, Rose, Frank, Fink, Ludger, Seeger, Werner, Schaefer, Liliana, Günther, Andreas, Eickelberg, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662540/
https://ncbi.nlm.nih.gov/pubmed/19287097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33950
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