Pulmonary Epithelium Is a Prominent Source of Proteinase-activated Receptor-1–inducible CCL2 in Pulmonary Fibrosis

Rationale: Studies in patients and experimental animals provide compelling evidence of the involvement of the major thrombin receptor, proteinase-activated receptor-1 (PAR(1)), and the potent chemokine, chemokine (CC motif) ligand-2 (CCL2)/monocyte chemotactic protein-1, in the pathogenesis of idiop...

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Detalhes bibliográficos
Main Authors: Mercer, Paul F., Johns, Robin H., Scotton, Chris J., Krupiczojc, Malvina A., Königshoff, Melanie, Howell, David C. J., McAnulty, Robin J., Das, Anuk, Thorley, Andrew J., Tetley, Terry D., Eickelberg, Oliver, Chambers, Rachel C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2009
Assuntos:
F. Interstitial Lung Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648910/
https://ncbi.nlm.nih.gov/pubmed/19060230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200712-1827OC
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