Proteinase-Activated Receptor-1, CCL2, and CCL7 Regulate Acute Neutrophilic Lung Inflammation

PAR(1) plays a central role in mediating the interplay between coagulation and inflammation, but its role in regulating acute neutrophilic inflammation is unknown. We report that antagonism of PAR(1) was highly effective at reducing acute neutrophil accumulation in a mouse model of LPS-induced lung...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mercer, Paul F., Williams, Andrew E., Scotton, Christopher J., José, Ricardo J., Sulikowski, Michal, Moffatt, James D., Murray, Lynne A., Chambers, Rachel C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Thoracic Society 2014
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930934/
https://ncbi.nlm.nih.gov/pubmed/23972264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0142OC
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