The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton...

מאת Johannissen, Linus O., Scrutton, Nigel S., Sutcliffe, Michael J.
יצא לאור 2008

Barrier Compression and Its Contribution to Both Classical and Quantum Mechanical Aspects of Enzyme Catalysis

מאת Hay, Sam, Johannissen, Linus O., Sutcliffe, Michael J., Scrutton, Nigel S.
יצא לאור 2010

Coupled Motions Direct Electrons along Human Microsomal P450 Chains

מאת Pudney, Christopher R., Khara, Basile, Johannissen, Linus O., Scrutton, Nigel S.
יצא לאור 2011

Vertebrate Cryptochromes are Vestigial Flavoproteins

מאת Kutta, Roger J., Archipowa, Nataliya, Johannissen, Linus O., Jones, Alex R., Scrutton, Nigel S.
הוצא לאור ב Sci Rep (2017)

C3 and C6 Modification‐Specific OYE Biotransformations of Synthetic Carvones and Sequential BVMO Chemoenzymatic Synthesis of Chiral Caprolactones

מאת Issa, Issa S., Toogood, Helen S., Johannissen, Linus O., Raftery, James, Scrutton, Nigel S., Gardiner, John M.
הוצא לאור ב Chemistry (2019)

Identification of B cell epitopes enhanced by protein unfolding and aggregation

מאת Eyes, Timothy J., Austerberry, James I., Dearman, Rebecca J., Johannissen, Linus O., Kimber, Ian, Smith, Noel, Thistlethwaite, Angela, Derrick, Jeremy P.
הוצא לאור ב Mol Immunol (2019)

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

מאת Jeffreys, Laura N., Pacholarz, Kamila J., Johannissen, Linus O., Girvan, Hazel M., Barran, Perdita E., Voice, Michael W., Munro, Andrew W.
הוצא לאור ב J Biol Chem (2020)

Engineering an Efficient and Enantioselective Enzyme for the Morita-Baylis-Hillman Reaction

מאת Crawshaw, Rebecca, Crossley, Amy E., Johannissen, Linus, Burke, Ashleigh J., Hay, Sam, Levy, Colin, Baker, David, Lovelock, Sarah L., Green, Anthony P.
הוצא לאור ב Nat Chem (2022)

Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase

מאת Longbotham, James E., Levy, Colin, Johannissen, Linus O., Tarhonskaya, Hanna, Jiang, Shuo, Loenarz, Christoph, Flashman, Emily, Hay, Sam, Schofield, Christopher J., Scrutton, Nigel S.
הוצא לאור ב Biochemistry (2015)

Hydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems

מאת Sutcliffe, Michael J, Masgrau, Laura, Roujeinikova, Anna, Johannissen, Linus O, Hothi, Parvinder, Basran, Jaswir, Ranaghan, Kara E, Mulholland, Adrian J, Leys, David, Scrutton, Nigel S
יצא לאור 2006

Epoxyqueuosine Reductase Structure Suggests a Mechanism for Cobalamin-dependent tRNA Modification

מאת Payne, Karl A. P., Fisher, Karl, Sjuts, Hanno, Dunstan, Mark S., Bellina, Bruno, Johannissen, Linus, Barran, Perdita, Hay, Sam, Rigby, Stephen E. J., Leys, David
הוצא לאור ב J Biol Chem (2015)

Native mass spectrometry reveals the conformational diversity of the UVR8 photoreceptor

מאת Camacho, Inês S., Theisen, Alina, Johannissen, Linus O., Díaz-Ramos, L. Aranzazú, Christie, John M., Jenkins, Gareth I., Bellina, Bruno, Barran, Perdita, Jones, Alex R.
הוצא לאור ב Proc Natl Acad Sci U S A (2019)

Taming the Reactivity of Monoterpene Synthases To Guide Regioselective Product Hydroxylation

מאת Leferink, Nicole G. H., Ranaghan, Kara E., Battye, Jaime, Johannissen, Linus O., Hay, Sam, van der Kamp, Marc W., Mulholland, Adrian J., Scrutton, Nigel S.
הוצא לאור ב Chembiochem (2019)

Interplay between chromophore binding and domain assembly by the B(12)-dependent photoreceptor protein, CarH

מאת Camacho, Inês S., Black, Rachelle, Heyes, Derren J., Johannissen, Linus O., Ramakers, Lennart A. I., Bellina, Bruno, Barran, Perdita E., Hay, Sam, Jones, Alex R.
הוצא לאור ב Chem Sci (2021)

Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase

מאת Czarnota, Sylwia, Johannissen, Linus O., Baxter, Nicola J., Rummel, Felix, Wilson, Alex L., Cliff, Matthew J., Levy, Colin W., Scrutton, Nigel S., Waltho, Jonathan P., Hay, Sam
הוצא לאור ב ACS Catal (2019)

The photochemical mechanism of a B(12)-dependent photoreceptor protein

מאת Kutta, Roger J., Hardman, Samantha J. O., Johannissen, Linus O., Bellina, Bruno, Messiha, Hanan L., Ortiz-Guerrero, Juan Manuel, Elías-Arnanz, Montserrat, Padmanabhan, S., Barran, Perdita, Scrutton, Nigel S., Jones, Alex R.
הוצא לאור ב Nat Commun (2015)

Engineering the “Missing Link” in Biosynthetic (−)-Menthol Production: Bacterial Isopulegone Isomerase

מאת Currin, Andrew, Dunstan, Mark S., Johannissen, Linus O., Hollywood, Katherine A., Vinaixa, Maria, Jervis, Adrian J., Swainston, Neil, Rattray, Nicholas J. W., Gardiner, John M., Kell, Douglas B., Takano, Eriko, Toogood, Helen S., Scrutton, Nigel S.
הוצא לאור ב ACS Catal (2018)

Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase

מאת Karuppiah, Vijaykumar, Ranaghan, Kara E., Leferink, Nicole G. H., Johannissen, Linus O., Shanmugam, Muralidharan, Ní Cheallaigh, Aisling, Bennett, Nathan J., Kearsey, Lewis J., Takano, Eriko, Gardiner, John M., van der Kamp, Marc W., Hay, Sam, Mulholland, Adrian J., Leys, David, Scrutton, Nigel S.
הוצא לאור ב ACS Catal (2017)