The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton...

nork Johannissen, Linus O., Scrutton, Nigel S., Sutcliffe, Michael J.
Argitaratua 2008

Barrier Compression and Its Contribution to Both Classical and Quantum Mechanical Aspects of Enzyme Catalysis

nork Hay, Sam, Johannissen, Linus O., Sutcliffe, Michael J., Scrutton, Nigel S.
Argitaratua 2010

Coupled Motions Direct Electrons along Human Microsomal P450 Chains

nork Pudney, Christopher R., Khara, Basile, Johannissen, Linus O., Scrutton, Nigel S.
Argitaratua 2011

Vertebrate Cryptochromes are Vestigial Flavoproteins

nork Kutta, Roger J., Archipowa, Nataliya, Johannissen, Linus O., Jones, Alex R., Scrutton, Nigel S.
Argitaratua izan da Sci Rep (2017)

C3 and C6 Modification‐Specific OYE Biotransformations of Synthetic Carvones and Sequential BVMO Chemoenzymatic Synthesis of Chiral Caprolactones

nork Issa, Issa S., Toogood, Helen S., Johannissen, Linus O., Raftery, James, Scrutton, Nigel S., Gardiner, John M.
Argitaratua izan da Chemistry (2019)

Identification of B cell epitopes enhanced by protein unfolding and aggregation

nork Eyes, Timothy J., Austerberry, James I., Dearman, Rebecca J., Johannissen, Linus O., Kimber, Ian, Smith, Noel, Thistlethwaite, Angela, Derrick, Jeremy P.
Argitaratua izan da Mol Immunol (2019)

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

nork Jeffreys, Laura N., Pacholarz, Kamila J., Johannissen, Linus O., Girvan, Hazel M., Barran, Perdita E., Voice, Michael W., Munro, Andrew W.
Argitaratua izan da J Biol Chem (2020)

Engineering an Efficient and Enantioselective Enzyme for the Morita-Baylis-Hillman Reaction

nork Crawshaw, Rebecca, Crossley, Amy E., Johannissen, Linus, Burke, Ashleigh J., Hay, Sam, Levy, Colin, Baker, David, Lovelock, Sarah L., Green, Anthony P.
Argitaratua izan da Nat Chem (2022)

Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase

nork Longbotham, James E., Levy, Colin, Johannissen, Linus O., Tarhonskaya, Hanna, Jiang, Shuo, Loenarz, Christoph, Flashman, Emily, Hay, Sam, Schofield, Christopher J., Scrutton, Nigel S.
Argitaratua izan da Biochemistry (2015)

Hydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems

nork Sutcliffe, Michael J, Masgrau, Laura, Roujeinikova, Anna, Johannissen, Linus O, Hothi, Parvinder, Basran, Jaswir, Ranaghan, Kara E, Mulholland, Adrian J, Leys, David, Scrutton, Nigel S
Argitaratua 2006

Epoxyqueuosine Reductase Structure Suggests a Mechanism for Cobalamin-dependent tRNA Modification

nork Payne, Karl A. P., Fisher, Karl, Sjuts, Hanno, Dunstan, Mark S., Bellina, Bruno, Johannissen, Linus, Barran, Perdita, Hay, Sam, Rigby, Stephen E. J., Leys, David
Argitaratua izan da J Biol Chem (2015)

Native mass spectrometry reveals the conformational diversity of the UVR8 photoreceptor

nork Camacho, Inês S., Theisen, Alina, Johannissen, Linus O., Díaz-Ramos, L. Aranzazú, Christie, John M., Jenkins, Gareth I., Bellina, Bruno, Barran, Perdita, Jones, Alex R.
Argitaratua izan da Proc Natl Acad Sci U S A (2019)

Taming the Reactivity of Monoterpene Synthases To Guide Regioselective Product Hydroxylation

nork Leferink, Nicole G. H., Ranaghan, Kara E., Battye, Jaime, Johannissen, Linus O., Hay, Sam, van der Kamp, Marc W., Mulholland, Adrian J., Scrutton, Nigel S.
Argitaratua izan da Chembiochem (2019)

Interplay between chromophore binding and domain assembly by the B(12)-dependent photoreceptor protein, CarH

nork Camacho, Inês S., Black, Rachelle, Heyes, Derren J., Johannissen, Linus O., Ramakers, Lennart A. I., Bellina, Bruno, Barran, Perdita E., Hay, Sam, Jones, Alex R.
Argitaratua izan da Chem Sci (2021)

Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase

nork Czarnota, Sylwia, Johannissen, Linus O., Baxter, Nicola J., Rummel, Felix, Wilson, Alex L., Cliff, Matthew J., Levy, Colin W., Scrutton, Nigel S., Waltho, Jonathan P., Hay, Sam
Argitaratua izan da ACS Catal (2019)

The photochemical mechanism of a B(12)-dependent photoreceptor protein

nork Kutta, Roger J., Hardman, Samantha J. O., Johannissen, Linus O., Bellina, Bruno, Messiha, Hanan L., Ortiz-Guerrero, Juan Manuel, Elías-Arnanz, Montserrat, Padmanabhan, S., Barran, Perdita, Scrutton, Nigel S., Jones, Alex R.
Argitaratua izan da Nat Commun (2015)

Engineering the “Missing Link” in Biosynthetic (−)-Menthol Production: Bacterial Isopulegone Isomerase

nork Currin, Andrew, Dunstan, Mark S., Johannissen, Linus O., Hollywood, Katherine A., Vinaixa, Maria, Jervis, Adrian J., Swainston, Neil, Rattray, Nicholas J. W., Gardiner, John M., Kell, Douglas B., Takano, Eriko, Toogood, Helen S., Scrutton, Nigel S.
Argitaratua izan da ACS Catal (2018)

Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase

nork Karuppiah, Vijaykumar, Ranaghan, Kara E., Leferink, Nicole G. H., Johannissen, Linus O., Shanmugam, Muralidharan, Ní Cheallaigh, Aisling, Bennett, Nathan J., Kearsey, Lewis J., Takano, Eriko, Gardiner, John M., van der Kamp, Marc W., Hay, Sam, Mulholland, Adrian J., Leys, David, Scrutton, Nigel S.
Argitaratua izan da ACS Catal (2017)