The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton...

af Johannissen, Linus O., Scrutton, Nigel S., Sutcliffe, Michael J.
Udgivet 2008

Barrier Compression and Its Contribution to Both Classical and Quantum Mechanical Aspects of Enzyme Catalysis

af Hay, Sam, Johannissen, Linus O., Sutcliffe, Michael J., Scrutton, Nigel S.
Udgivet 2010

Coupled Motions Direct Electrons along Human Microsomal P450 Chains

af Pudney, Christopher R., Khara, Basile, Johannissen, Linus O., Scrutton, Nigel S.
Udgivet 2011

Vertebrate Cryptochromes are Vestigial Flavoproteins

af Kutta, Roger J., Archipowa, Nataliya, Johannissen, Linus O., Jones, Alex R., Scrutton, Nigel S.
Udgivet i Sci Rep (2017)

C3 and C6 Modification‐Specific OYE Biotransformations of Synthetic Carvones and Sequential BVMO Chemoenzymatic Synthesis of Chiral Caprolactones

af Issa, Issa S., Toogood, Helen S., Johannissen, Linus O., Raftery, James, Scrutton, Nigel S., Gardiner, John M.
Udgivet i Chemistry (2019)

Identification of B cell epitopes enhanced by protein unfolding and aggregation

af Eyes, Timothy J., Austerberry, James I., Dearman, Rebecca J., Johannissen, Linus O., Kimber, Ian, Smith, Noel, Thistlethwaite, Angela, Derrick, Jeremy P.
Udgivet i Mol Immunol (2019)

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

af Jeffreys, Laura N., Pacholarz, Kamila J., Johannissen, Linus O., Girvan, Hazel M., Barran, Perdita E., Voice, Michael W., Munro, Andrew W.
Udgivet i J Biol Chem (2020)

Engineering an Efficient and Enantioselective Enzyme for the Morita-Baylis-Hillman Reaction

af Crawshaw, Rebecca, Crossley, Amy E., Johannissen, Linus, Burke, Ashleigh J., Hay, Sam, Levy, Colin, Baker, David, Lovelock, Sarah L., Green, Anthony P.
Udgivet i Nat Chem (2022)

Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase

af Longbotham, James E., Levy, Colin, Johannissen, Linus O., Tarhonskaya, Hanna, Jiang, Shuo, Loenarz, Christoph, Flashman, Emily, Hay, Sam, Schofield, Christopher J., Scrutton, Nigel S.
Udgivet i Biochemistry (2015)

Hydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems

af Sutcliffe, Michael J, Masgrau, Laura, Roujeinikova, Anna, Johannissen, Linus O, Hothi, Parvinder, Basran, Jaswir, Ranaghan, Kara E, Mulholland, Adrian J, Leys, David, Scrutton, Nigel S
Udgivet 2006

Epoxyqueuosine Reductase Structure Suggests a Mechanism for Cobalamin-dependent tRNA Modification

af Payne, Karl A. P., Fisher, Karl, Sjuts, Hanno, Dunstan, Mark S., Bellina, Bruno, Johannissen, Linus, Barran, Perdita, Hay, Sam, Rigby, Stephen E. J., Leys, David
Udgivet i J Biol Chem (2015)

Native mass spectrometry reveals the conformational diversity of the UVR8 photoreceptor

af Camacho, Inês S., Theisen, Alina, Johannissen, Linus O., Díaz-Ramos, L. Aranzazú, Christie, John M., Jenkins, Gareth I., Bellina, Bruno, Barran, Perdita, Jones, Alex R.
Udgivet i Proc Natl Acad Sci U S A (2019)

Taming the Reactivity of Monoterpene Synthases To Guide Regioselective Product Hydroxylation

af Leferink, Nicole G. H., Ranaghan, Kara E., Battye, Jaime, Johannissen, Linus O., Hay, Sam, van der Kamp, Marc W., Mulholland, Adrian J., Scrutton, Nigel S.
Udgivet i Chembiochem (2019)

Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase

af Czarnota, Sylwia, Johannissen, Linus O., Baxter, Nicola J., Rummel, Felix, Wilson, Alex L., Cliff, Matthew J., Levy, Colin W., Scrutton, Nigel S., Waltho, Jonathan P., Hay, Sam
Udgivet i ACS Catal (2019)

The photochemical mechanism of a B(12)-dependent photoreceptor protein

af Kutta, Roger J., Hardman, Samantha J. O., Johannissen, Linus O., Bellina, Bruno, Messiha, Hanan L., Ortiz-Guerrero, Juan Manuel, Elías-Arnanz, Montserrat, Padmanabhan, S., Barran, Perdita, Scrutton, Nigel S., Jones, Alex R.
Udgivet i Nat Commun (2015)

Engineering the “Missing Link” in Biosynthetic (−)-Menthol Production: Bacterial Isopulegone Isomerase

af Currin, Andrew, Dunstan, Mark S., Johannissen, Linus O., Hollywood, Katherine A., Vinaixa, Maria, Jervis, Adrian J., Swainston, Neil, Rattray, Nicholas J. W., Gardiner, John M., Kell, Douglas B., Takano, Eriko, Toogood, Helen S., Scrutton, Nigel S.
Udgivet i ACS Catal (2018)

Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase

af Karuppiah, Vijaykumar, Ranaghan, Kara E., Leferink, Nicole G. H., Johannissen, Linus O., Shanmugam, Muralidharan, Ní Cheallaigh, Aisling, Bennett, Nathan J., Kearsey, Lewis J., Takano, Eriko, Gardiner, John M., van der Kamp, Marc W., Hay, Sam, Mulholland, Adrian J., Leys, David, Scrutton, Nigel S.
Udgivet i ACS Catal (2017)