Understanding the Complexity of Porous Graphitic Carbon (PGC) Chromatography: Modulation of Mobile-Stationary Phase Interactions Overcomes Loss of Retention and Reduces Variability

Por Bapiro, Tashinga E., Richards, Frances M., Jodrell, Duncan I.
Publicado no Anal Chem (2016)

Efficacy, safety, and cost of new anticancer drugs : Pessimistic conclusion was not justified

Por Calvert, Hilary, Jodrell, Duncan I, Cassidy, James, Harris, Adrian L
Publicado em 2002

Anti-Tumour Effects of a Specific Anti-ADAM17 Antibody in an Ovarian Cancer Model In Vivo

Por Richards, Frances M., Tape, Christopher J., Jodrell, Duncan I., Murphy, Gillian
Publicado em 2012

GEMMs as preclinical models for testing pancreatic cancer therapies

Por Gopinathan, Aarthi, Morton, Jennifer P., Jodrell, Duncan I., Sansom, Owen J.
Publicado no Dis Model Mech (2015)

Optimization of the Antitumor Activity of Sequence-specific Pyrrolobenzodiazepine Derivatives Based on their Affinity for ABC Transporters

Por Kaliszczak, Maciej, Antonow, Dyeison, Patel, Katan I., Howard, Philip, Jodrell, Duncan I., Thurston, David E., Guichard, Sylvie M.
Publicado em 2010

Modelling of the cancer cell cycle as a tool for rational drug development: A systems pharmacology approach to cyclotherapy

Por Jackson, Robert C., Di Veroli, Giovanni Y., Koh, Siang-Boon, Goldlust, Ian, Richards, Frances M., Jodrell, Duncan I.
Publicado no PLoS Comput Biol (2017)

nab-paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer

Por Frese, Kristopher K., Neesse, Albrecht, Cook, Natalie, Bapiro, Tashinga E., Lolkema, Martijn P., Jodrell, Duncan I., Tuveson, David A.
Publicado no Cancer Discov (2012)

Combenefit: an interactive platform for the analysis and visualization of drug combinations

Por Di Veroli, Giovanni Y., Fornari, Chiara, Wang, Dennis, Mollard, Séverine, Bramhall, Jo L., Richards, Frances M., Jodrell, Duncan I.
Publicado no Bioinformatics (2016)

An automated fitting procedure and software for dose-response curves with multiphasic features

Por Veroli, Giovanni Y. Di, Fornari, Chiara, Goldlust, Ian, Mills, Graham, Koh, Siang Boon, Bramhall, Jo L, Richards, Frances M., Jodrell, Duncan I.
Publicado no Sci Rep (2015)

Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity

Por Flint, Thomas R., Janowitz, Tobias, Connell, Claire M., Roberts, Edward W., Denton, Alice E., Coll, Anthony P., Jodrell, Duncan I., Fearon, Douglas T.
Publicado no Cell Metab (2016)

Cancer Immunotherapy Trials Underutilize Immune Response Monitoring

Por Connell, Claire M., Raby, Sophie E.M., Beh, Ian, Flint, Thomas R., Williams, Edward H., Fearon, Douglas T., Jodrell, Duncan I., Janowitz, Tobias
Publicado no Oncologist (2017)

Mechanistic distinctions between CHK1 and WEE1 inhibition guide the scheduling of triple therapy with gemcitabine

Por Koh, Siang-Boon, Wallez, Yann, Dunlop, Charles R, de Quirós Fernández, Sandra Bernaldo, Bapiro, Tashinga E, Richards, Frances M, Jodrell, Duncan I
Publicado no Cancer Res (2018)

Anti-Tumour Efficacy of Capecitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer

Por Courtin, Aurélie, Richards, Frances M., Bapiro, Tashinga E., Bramhall, Jo L., Neesse, Albrecht, Cook, Natalie, Krippendorff, Ben-Fillippo, Tuveson, David A., Jodrell, Duncan I.
Publicado em 2013

SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice

Por Neesse, Albrecht, Frese, Kristopher K, Chan, Derek S, Bapiro, Tashinga E, Howat, William J, Richards, Frances M, Ellenrieder, Volker, Jodrell, Duncan I, Tuveson, David A
Publicado em 2014

The use of error-category mapping in pharmacokinetic model analysis of dynamic contrast-enhanced MRI data

Por Gill, Andrew B., Anandappa, Gayathri, Patterson, Andrew J., Priest, Andrew N., Graves, Martin J., Janowitz, Tobias, Jodrell, Duncan I., Eisen, Tim, Lomas, David J.
Publicado no Magn Reson Imaging (2015)

CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer

Por Neesse, Albrecht, Frese, Kristopher K., Bapiro, Tashinga E., Nakagawa, Tomoaki, Sternlicht, Mark D., Seeley, Todd W., Pilarsky, Christian, Jodrell, Duncan I., Spong, Suzanne M., Tuveson, David A.
Publicado em 2013

Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma

Por Cook, Natalie, Frese, Kristopher K., Bapiro, Tashinga E., Jacobetz, Michael A., Gopinathan, Aarthi, Miller, Jodi L., Rao, Sudhir S., Demuth, Tim, Howat, William J., Jodrell, Duncan I., Tuveson, David A.
Publicado em 2012

Design, Synthesis, and Biological Evaluation of an Allosteric Inhibitor of HSET that Targets Cancer Cells with Supernumerary Centrosomes

Por Watts, Ciorsdaidh A., Richards, Frances M., Bender, Andreas, Bond, Peter J., Korb, Oliver, Kern, Oliver, Riddick, Michelle, Owen, Paul, Myers, Rebecca M., Raff, Jordan, Gergely, Fanni, Jodrell, Duncan I., Ley, Steven V.
Publicado em 2013

New Model for Estimating Glomerular Filtration Rate in Patients With Cancer

Por Janowitz, Tobias, Williams, Edward H., Marshall, Andrea, Ainsworth, Nicola, Thomas, Peter B., Sammut, Stephen J., Shepherd, Scott, White, Jeff, Mark, Patrick B., Lynch, Andy G., Jodrell, Duncan I., Tavaré, Simon, Earl, Helena
Publicado no J Clin Oncol (2017)

A novel method for quantification of gemcitabine and its metabolites 2′,2′-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC–MS/MS: comparison with (19)F NMR...

Por Bapiro, Tashinga E., Richards, Frances M., Goldgraben, Mae A., Olive, Kenneth P., Madhu, Basetti, Frese, Kristopher K., Cook, Natalie, Jacobetz, Michael A., Smith, Donna-Michelle, Tuveson, David A., Griffiths, John R., Jodrell, Duncan I.
Publicado em 2011