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Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity
In patients with cancer, the wasting syndrome, cachexia, is associated with caloric deficiency. Here, we describe tumor-induced alterations of the host metabolic response to caloric deficiency that cause intratumoral immune suppression. In pre-cachectic mice with transplanted colorectal cancer or au...
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Publicado no: | Cell Metab |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cell Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5106372/ https://ncbi.nlm.nih.gov/pubmed/27829137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.10.010 |
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