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Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8(+) T cells

Fibroblastic reticular cells (FRCs), through their expression of CC chemokine ligand (CCL)19 and CCL21, attract and retain T cells in lymph nodes (LNs), but whether this function applies to both resting and activated T cells has not been examined. Here we describe a model for conditionally depleting...

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Bibliographische Detailangaben
Hauptverfasser: Denton, Alice E., Roberts, Edward W., Linterman, Michelle A., Fearon, Douglas T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143042/
https://ncbi.nlm.nih.gov/pubmed/25092322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412910111
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