Embryonic FAP(+) lymphoid tissue organizer cells generate the reticular network of adult lymph nodes

The induction of adaptive immunity is dependent on the structural organization of LNs, which is in turn governed by the stromal cells that underpin LN architecture. Using a novel fate-mapping mouse model, we trace the developmental origin of mesenchymal LN stromal cells (mLNSCs) to a previously unde...

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Vydáno v:J Exp Med
Hlavní autoři: Denton, Alice E., Carr, Edward J., Magiera, Lukasz P., Watts, Andrew J.B., Fearon, Douglas T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780995/
https://ncbi.nlm.nih.gov/pubmed/31324739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181705
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