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Embryonic FAP(+) lymphoid tissue organizer cells generate the reticular network of adult lymph nodes

The induction of adaptive immunity is dependent on the structural organization of LNs, which is in turn governed by the stromal cells that underpin LN architecture. Using a novel fate-mapping mouse model, we trace the developmental origin of mesenchymal LN stromal cells (mLNSCs) to a previously unde...

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Med
Hauptverfasser: Denton, Alice E., Carr, Edward J., Magiera, Lukasz P., Watts, Andrew J.B., Fearon, Douglas T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780995/
https://ncbi.nlm.nih.gov/pubmed/31324739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181705
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