SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice

DESIGN: Pharmacokinetic and pharmacodynamic parameters of cremophor-paclitaxel, nab-paclitaxel (human-albumin-bound paclitaxel, Abraxane) and a novel mouse-albumin-bound paclitaxel (m-nab-paclitaxel) were evaluated in genetically engineered mouse models (GEMMs) by liquid chromatography-tandem mass s...

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Detalhes bibliográficos
Main Authors: Neesse, Albrecht, Frese, Kristopher K, Chan, Derek S, Bapiro, Tashinga E, Howat, William J, Richards, Frances M, Ellenrieder, Volker, Jodrell, Duncan I, Tuveson, David A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Pancreatic Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033275/
https://ncbi.nlm.nih.gov/pubmed/24067278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-305559
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