Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization.

Por Goedert, M, Jakes, R
Publicado em 1990

The primary structure of alamethicin

Por Payne, J. W., Jakes, R., Hartley, B. S.
Publicado em 1970

Mapping the cysteine residues and actin-binding regions of villin by using antisera to the amino and carboxyl termini of the molecule.

Por Matsudaira, P, Jakes, R, Cameron, L, Atherton, E
Publicado em 1985

Different configurational states of beta-amyloid and their distributions relative to plaques and tangles in Alzheimer disease.

Por Spillantini, M G, Goedert, M, Jakes, R, Klug, A
Publicado em 1990

Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease.

Por Spillantini, M G, Goedert, M, Jakes, R, Klug, A
Publicado em 1990

Identification of 3- and 4-repeat tau isoforms within the PHF in Alzheimer's disease.

Por Jakes, R, Novak, M, Davison, M, Wischik, C M
Publicado em 1991

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of ot...

Por Goedert, M, Cuenda, A, Craxton, M, Jakes, R, Cohen, P
Publicado em 1997

Interaction of dense breast patterns with other breast cancer risk factors in a case–control study

Por Duffy, S W, Jakes, R W, Ng, F C, Gao, F
Publicado em 2004

Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.51.

Por Novak, M, Jakes, R, Edwards, P C, Milstein, C, Wischik, C M
Publicado em 1991

Villin sequence and peptide map identify six homologous domains.

Por Bazari, W L, Matsudaira, P, Wallek, M, Smeal, T, Jakes, R, Ahmed, Y
Publicado em 1988

Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform.

Por Götz, J, Probst, A, Spillantini, M G, Schäfer, T, Jakes, R, Bürki, K, Goedert, M
Publicado em 1995

Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-35...

Por Litersky, J M, Johnson, G V, Jakes, R, Goedert, M, Lee, M, Seubert, P
Publicado em 1996

Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein.

Por Goedert, M, Jakes, R, Crowther, R A, Cohen, P, Vanmechelen, E, Vandermeeren, M, Cras, P
Publicado em 1994

The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycoge...

Por Woods, Y L, Cohen, P, Becker, W, Jakes, R, Goedert, M, Wang, X, Proud, C G
Publicado em 2001

Mammographic density and its interaction with other breast cancer risk factors in an Asian population

Por Wong, C S, Lim, G H, Gao, F, Jakes, R W, Offman, J, Chia, K S, Duffy, S W
Publicado em 2011

From genetics to pathology: tau and alpha-synuclein assemblies in neurodegenerative diseases.

Por Goedert, M, Spillantini, M G, Serpell, L C, Berriman, J, Smith, M J, Jakes, R, Crowther, R A
Publicado em 2001

Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NAC.

Por Jensen, P H, Hojrup, P, Hager, H, Nielsen, M S, Jacobsen, L, Olesen, O F, Gliemann, J, Jakes, R
Publicado em 1997

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development.

Por Goedert, M, Jakes, R, Crowther, R A, Six, J, Lübke, U, Vandermeeren, M, Cras, P, Trojanowski, J Q, Lee, V M
Publicado em 1993

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease.

Por Wischik, C M, Novak, M, Thøgersen, H C, Edwards, P C, Runswick, M J, Jakes, R, Walker, J E, Milstein, C, Roth, M, Klug, A
Publicado em 1988

Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease.

Por Strittmatter, W J, Saunders, A M, Goedert, M, Weisgraber, K H, Dong, L M, Jakes, R, Huang, D Y, Pericak-Vance, M, Schmechel, D, Roses, A D
Publicado em 1994