Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform.

Microtubule-associated protein tau is the major constituent of the paired helical filament, the main fibrous component of the neurofibrillary lesions of Alzheimer's disease. Tau is an axonal phosphoprotein in normal adult brain. In Alzheimer's disease brain tau is hyperphosphorylated and is found no...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Götz, J, Probst, A, Spillantini, M G, Schäfer, T, Jakes, R, Bürki, K, Goedert, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7729409/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07116.x
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