Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform.

Microtubule-associated protein tau is the major constituent of the paired helical filament, the main fibrous component of the neurofibrillary lesions of Alzheimer's disease. Tau is an axonal phosphoprotein in normal adult brain. In Alzheimer's disease brain tau is hyperphosphorylated and is found no...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Götz, J, Probst, A, Spillantini, M G, Schäfer, T, Jakes, R, Bürki, K, Goedert, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7729409/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07116.x
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