Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein.

Tau is a neuronal phosphoprotein the expression of which is developmentally regulated. A single tau isoform is expressed in fetal human brain but six isoforms are expressed in adult human brain, with the fetal isoform corresponding to the shortest adult isoform. Phosphorylation is also developmental...

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Bibliographic Details
Main Authors: Goedert, M, Jakes, R, Crowther, R A, Cohen, P, Vanmechelen, E, Vandermeeren, M, Cras, P
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137067/
https://ncbi.nlm.nih.gov/pubmed/7519852
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