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Image reconstruction of the Alzheimer paired helical filament.

The paired helical filament (PHF) is the principal constituent of the neurofibrillary tangles that occur in the brain in senile dementias of the Alzheimer type. We have previously shown from fragmentation patterns of isolated PHFs that they consist of a regularly repeating subunit, which is axially...

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Autori principali: Crowther, R A, Wischik, C M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC554715/
https://ncbi.nlm.nih.gov/pubmed/2419127
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