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Structural characterization of the core of the paired helical filament of Alzheimer disease.
The paired helical filament, the principal constituent of the neurofibrillary tangles characteristic of Alzheimer disease, is shown to consist of two structurally distinct parts. An external fuzzy region can be removed by Pronase treatment to leave a Pronase-resistant morphologically recognizable co...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280541/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2455299/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4884 |
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