Identification and localization of a tau peptide to paired helical filaments of Alzheimer disease.

Amino acid sequencing of a CNBr digest of the tau protein isolated from bovine brain revealed an amino acid sequence of 17 residues, Pro-Gly-Leu-Lys-Glu-Ser-Pro-Leu-Gln-Ile-Gly-Ala-Ala-Pro-Gly-Leu-Lys, which we call peptide I, with heterogeneity at position 11 of glycine (peptide Ia) and proline (pe...

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Main Authors: Iqbal, K, Grundke-Iqbal, I, Smith, A J, George, L, Tung, Y C, Zaidi, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC297681/
https://ncbi.nlm.nih.gov/pubmed/2501795
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