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Identification and localization of a tau peptide to paired helical filaments of Alzheimer disease.

Amino acid sequencing of a CNBr digest of the tau protein isolated from bovine brain revealed an amino acid sequence of 17 residues, Pro-Gly-Leu-Lys-Glu-Ser-Pro-Leu-Gln-Ile-Gly-Ala-Ala-Pro-Gly-Leu-Lys, which we call peptide I, with heterogeneity at position 11 of glycine (peptide Ia) and proline (pe...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Iqbal, K, Grundke-Iqbal, I, Smith, A J, George, L, Tung, Y C, Zaidi, T
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297681/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2501795/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.14.5646
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