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Structural characterization of the core of the paired helical filament of Alzheimer disease.

The paired helical filament, the principal constituent of the neurofibrillary tangles characteristic of Alzheimer disease, is shown to consist of two structurally distinct parts. An external fuzzy region can be removed by Pronase treatment to leave a Pronase-resistant morphologically recognizable co...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Wischik, C M, Novak, M, Edwards, P C, Klug, A, Tichelaar, W, Crowther, R A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1988
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280541/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2455299/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4884
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