Therapeutically targeting guanylate cyclase‐C: computational modeling of plecanatide, a uroguanylin analog

Por Brancale, Andrea, Shailubhai, Kunwar, Ferla, Salvatore, Ricci, Antonio, Bassetto, Marcella, Jacob, Gary S
Publicado no Pharmacol Res Perspect (2017)

Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis

Por Shailubhai, Kunwar, Palejwala, Vaseem, Arjunan, Krishna Priya, Saykhedkar, Sayali, Nefsky, Bradley, Foss, John A, Comiskey, Stephen, Jacob, Gary S, Plevy, Scott E
Publicado no World J Gastrointest Pharmacol Ther (2015)

Virulence of a Phosphoribosylaminoimidazole Carboxylase-Deficient Candida albicans Strain in an Immunosuppressed Murine Model of Systemic Candidiasis

Por Donovan, Matthew, Schumuke, Jon J., Fonzi, William A., Bonar, Sheri L., Gheesling-Mullis, Karen, Jacob, Gary S., Davisson, Vincent Jo, Dotson, Stanton B.
Publicado em 2001

A clinically relevant SCID-hu in vivo model of human multiple myeloma

Por Tassone, Pierfrancesco, Neri, Paola, Carrasco, Daniel R., Burger, Renate, Goldmacher, Victor S., Fram, Robert, Munshi, Vidit, Shammas, Masood A., Catley, Laurence, Jacob, Gary S., Venuta, Salvatore, Anderson, Kenneth C., Munshi, Nikhil C.
Publicado em 2005

Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo

Por Hamasaki, Makoto, Hideshima, Teru, Tassone, Pierfrancesco, Neri, Paola, Ishitsuka, Kenji, Yasui, Hiroshi, Shiraishi, Norihiko, Raje, Noopur, Kumar, Shaji, Picker, Donald H., Jacob, Gary S., Richardson, Paul G., Munshi, Nikhil C., Anderson, Kenneth C.
Publicado em 2005