A clinically relevant SCID-hu in vivo model of human multiple myeloma

We developed a novel in vivo multiple myeloma (MM) model by engrafting the interleukin 6 (IL-6)-dependent human MM cell line INA-6 into severe combined immunodeficiency (SCID) mice previously given implants of a human fetal bone chip (SCID-hu mice). INA-6 cells require either exogenous human IL-6 (h...

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Detalhes bibliográficos
Main Authors: Tassone, Pierfrancesco, Neri, Paola, Carrasco, Daniel R., Burger, Renate, Goldmacher, Victor S., Fram, Robert, Munshi, Vidit, Shammas, Masood A., Catley, Laurence, Jacob, Gary S., Venuta, Salvatore, Anderson, Kenneth C., Munshi, Nikhil C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895174/
https://ncbi.nlm.nih.gov/pubmed/15817674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0373
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