Virulence of a Phosphoribosylaminoimidazole Carboxylase-Deficient Candida albicans Strain in an Immunosuppressed Murine Model of Systemic Candidiasis

The relative pathogenicities of three Candida albicans strains differing in the function of ADE2 (the gene encoding phosphoribosylaminoimidazole carboxylase) were evaluated in a murine candidiasis model. C. albicans strain CAI7 (ade2/ade2), previously constructed by site-specific recombination, was...

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Detalhes bibliográficos
Main Authors: Donovan, Matthew, Schumuke, Jon J., Fonzi, William A., Bonar, Sheri L., Gheesling-Mullis, Karen, Jacob, Gary S., Davisson, Vincent Jo, Dotson, Stanton B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98190/
https://ncbi.nlm.nih.gov/pubmed/11254618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2542-2548.2001
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