Virulence of a Phosphoribosylaminoimidazole Carboxylase-Deficient Candida albicans Strain in an Immunosuppressed Murine Model of Systemic Candidiasis

The relative pathogenicities of three Candida albicans strains differing in the function of ADE2 (the gene encoding phosphoribosylaminoimidazole carboxylase) were evaluated in a murine candidiasis model. C. albicans strain CAI7 (ade2/ade2), previously constructed by site-specific recombination, was...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Autores principales:	Donovan, Matthew, Schumuke, Jon J., Fonzi, William A., Bonar, Sheri L., Gheesling-Mullis, Karen, Jacob, Gary S., Davisson, Vincent Jo, Dotson, Stanton B.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Materias:	Fungal and Parasitic Infections
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98190/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11254618/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.4.2542-2548.2001
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