Virulence of a Phosphoribosylaminoimidazole Carboxylase-Deficient Candida albicans Strain in an Immunosuppressed Murine Model of Systemic Candidiasis

The relative pathogenicities of three Candida albicans strains differing in the function of ADE2 (the gene encoding phosphoribosylaminoimidazole carboxylase) were evaluated in a murine candidiasis model. C. albicans strain CAI7 (ade2/ade2), previously constructed by site-specific recombination, was...

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Main Authors: Donovan, Matthew, Schumuke, Jon J., Fonzi, William A., Bonar, Sheri L., Gheesling-Mullis, Karen, Jacob, Gary S., Davisson, Vincent Jo, Dotson, Stanton B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Fungal and Parasitic Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC98190/
https://ncbi.nlm.nih.gov/pubmed/11254618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2542-2548.2001
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