Chemical Modification of Linkers Provides Stable Linker–Payloads for the Generation of Antibody–Drug Conjugates

由 Poudel, Yam B., Chowdari, Naidu S., Cheng, Heng, Iwuagwu, Christiana I., King, H. Dalton, Kotapati, Srikanth, Passmore, David, Rampulla, Richard, Mathur, Arvind, Vite, Gregory, Gangwar, Sanjeev
發表在 ACS Med Chem Lett (2020)

The Novel, Nicotinic Alpha7 Receptor Partial Agonist, BMS-933043, Improves Cognition and Sensory Processing in Preclinical Models of Schizophrenia

由 Bristow, Linda J., Easton, Amy E., Li, Yu-Wen, Sivarao, Digavalli V., Lidge, Regina, Jones, Kelli M., Post-Munson, Debra, Daly, Christopher, Lodge, Nicholas J., Gallagher, Lizbeth, Molski, Thaddeus, Pieschl, Richard, Chen, Ping, Hendricson, Adam, Westphal, Ryan, Cook, James, Iwuagwu, Christiana, Morgan, Daniel, Benitex, Yulia, King, Dalton, Macor, John E., Zaczek, Robert, Olson, Richard
發表在 PLoS One (2016)

Development of 4-Heteroarylamino-1′-azaspiro[oxazole-5,3′-bicyclo[2.2.2]octanes] as α7 Nicotinic Receptor Agonists

由 Hill, Matthew D., Fang, Haiquan, King, H. Dalton, Iwuagwu, Christiana I., McDonald, Ivar M., Cook, James, Zusi, F. Christopher, Mate, Robert A., Knox, Ronald J., Post-Munson, Debra, Easton, Amy, Miller, Regina, Lentz, Kimberley, Clarke, Wendy, Benitex, Yulia, Lodge, Nicholas, Zaczek, Robert, Denton, Rex, Morgan, Daniel, Bristow, Linda, Macor, John E., Olson, Richard
發表在 ACS Med Chem Lett (2016)

BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia

由 King, Dalton, Iwuagwu, Christiana, Cook, Jim, McDonald, Ivar M., Mate, Robert, Zusi, F. Christopher, Hill, Matthew D., Fang, Haiquan, Zhao, Rulin, Wang, Bei, Easton, Amy E., Miller, Regina, Post-Munson, Debra, Knox, Ronald J., Gallagher, Lizbeth, Westphal, Ryan, Molski, Thaddeus, Fan, Jingsong, Clarke, Wendy, Benitex, Yulia, Lentz, Kimberley A., Denton, Rex, Morgan, Daniel, Zaczek, Robert, Lodge, Nicholas J., Bristow, Linda J., Macor, John E., Olson, Richard E.
發表在 ACS Med Chem Lett (2017)

DNA-Model-Based Design and Execution of Some Fused Benzodiazepine Hybrid Payloads for Antibody–Drug Conjugate Modality

由 Sivaprakasam, Prasanna, McDonald, Ivar, Iwuagwu, Christiana, Chowdari, Naidu S., Peese, Kevin M., Langley, David R., Cheng, Heng, Luzung, Michael R., Schmidt, Michael A., Zheng, Bin, Tan, Yichen, Cho, Patricia, Rakshit, Souvik, Lakshminarasimhan, Thirumalai, Guturi, Sivakrishna, Kanagavel, Kishorekumar, Kanusu, Umamaheswararao, Niyogi, Ankita G., Sidhar, Somprabha, Vaidyanathan, Rajappa, Eastgate, Martin D., Kotapati, Srikanth, Deshpande, Madhura, Pan, Chin, Cardarelli, Pina M., Xie, Chunshan, Rao, Chetana, Holder, Patrick, Sarma, Ganapathy, Vite, Gregory, Gangwar, Sanjeev
發表在 ACS Med Chem Lett (2021)