Synthetic Studies Toward Bryostatin 1: Preparation of a C(1)-C(16) Fragment by Pyran Annulation

di Keck, Gary E., Welch, Dennie S., Poudel, Yam B.
Pubblicazione 2006

A Pd(0)-Mediated Indole (Macro)cyclization Reaction

di Breazzano, Steven P., Poudel, Yam B., Boger, Dale L.
Pubblicazione 2013

Total synthesis of dihydrolysergic acid and dihydrolysergol: development of a divergent synthetic strategy applicable to rapid assembly of D-ring analogs

di Lee, Kiyoun, Poudel, Yam B., Glinkerman, Christopher M., Boger, Dale L.
Pubblicato in Tetrahedron (2015)

Total Synthesis of Bryostatin 1

di Keck, Gary E., Poudel, Yam B., Cummins, Thomas J., Rudra, Arnab, Covel, Jonathan A.
Pubblicazione 2010

Role of the C(8) gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity

di Keck, Gary E., Poudel, Yam B., Rudra, Arnab, Stephens, Jeffrey C., Kedei, Noemi, Lewin, Nancy E., Blumberg, Peter M.
Pubblicazione 2012

Synthesis of a des-B-Ring Bryostatin Analogue Leads to an Unexpected Ring Expansion of the Bryolactone Core

di Kraft, Matthew B., Poudel, Yam B., Kedei, Noemi, Lewin, Nancy E., Peach, Megan L., Blumberg, Peter M., Keck, Gary E.
Pubblicazione 2014

Molecular Modeling, Total Synthesis, and Biological Evaluations of C9-Deoxy Bryostatin 1

di Keck, Gary E., Poudel, Yam B., Rudra, Arnab, Stephens, Jeffrey C., Kedei, Noemi, Lewin, Nancy E., Peach, Megan L., Blumberg, Peter M.
Pubblicazione 2010

Substitution on the A-Ring Confers to Bryopyran Analogues the Unique Biological Activity Characteristic of Bryostatins and Distinct From That of the Phorbol Esters

di Keck, Gary E., Poudel, Yam B., Welch, Dennie S., Kraft, Matthew B., Truong, Anh P., Stephens, Jeffrey C., Kedei, Noemi, Lewin, Nancy E., Blumberg, Peter M.
Pubblicazione 2009

Chemical Modification of Linkers Provides Stable Linker–Payloads for the Generation of Antibody–Drug Conjugates

di Poudel, Yam B., Chowdari, Naidu S., Cheng, Heng, Iwuagwu, Christiana I., King, H. Dalton, Kotapati, Srikanth, Passmore, David, Rampulla, Richard, Mathur, Arvind, Vite, Gregory, Gangwar, Sanjeev
Pubblicato in ACS Med Chem Lett (2020)

The Biological Profile of the Less Lipophilic and Synthetically More Accessible Bryostatin 7 Closely Resembles That of Bryostatin 1

di Kedei, Noemi, Lewin, Nancy E., Geczy, Tamas, Selezneva, Julia, Braun, Derek C., Chen, Jinqiu, Herrmann, Michelle A., Heldman, Madeleine R., Lim, Langston, Mannan, Poonam, Garfield, Susan, Poudel, Yam B., Cummins, Thomas J., Rudra, Arnab, Blumberg, Peter M., Keck, Gary E.
Pubblicazione 2013