Substitution on the A-Ring Confers to Bryopyran Analogues the Unique Biological Activity Characteristic of Bryostatins and Distinct From That of the Phorbol Esters

Eitemau Tebyg

• Convergent Assembly of Highly Potent Analogues of Bryostatin 1 via Pyran Annulation: Bryostatin Look-alikes that Mimic Phorbol Ester Function
  gan: Keck, Gary E., et al.
  Cyhoeddwyd: (2008)
• The Bryostatin 1 A-Ring Acetate is Not the Critical Determinant for Antagonism of Phorbol Ester-Induced Biological Responses
  gan: Keck, Gary E., et al.
  Cyhoeddwyd: (2009)
• Synthesis of a des-B-Ring Bryostatin Analogue Leads to an Unexpected Ring Expansion of the Bryolactone Core
  gan: Kraft, Matthew B., et al.
  Cyhoeddwyd: (2014)
• Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogues in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action
  gan: Kedei, N., et al.
  Cyhoeddwyd: (2012)
• Role of the C(8) gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity
  gan: Keck, Gary E., et al.
  Cyhoeddwyd: (2012)