Convergent Assembly of Highly Potent Analogues of Bryostatin 1 via Pyran Annulation: Bryostatin Look-alikes that Mimic Phorbol Ester Function

Documenti analoghi

• The Bryostatin 1 A-Ring Acetate is Not the Critical Determinant for Antagonism of Phorbol Ester-Induced Biological Responses
  di: Keck, Gary E., et al.
  Pubblicazione: (2009)
• Substitution on the A-Ring Confers to Bryopyran Analogues the Unique Biological Activity Characteristic of Bryostatins and Distinct From That of the Phorbol Esters
  di: Keck, Gary E., et al.
  Pubblicazione: (2009)
• Synthetic Studies on the Bryostatins: Preparation of a Truncated BC-Ring Intermediate by Pyran Annulation
  di: Keck, Gary E., et al.
  Pubblicazione: (2005)
• Replacement of the Bryostatin A- and B-Pyran Rings With Phenyl Rings Leads to Loss of High Affinity Binding With PKC
  di: Petersen, Mark E., et al.
  Pubblicazione: (2016)
• Some phorbol esters may partially resemble bryostatin 1 in their actions on LNCaP prostate cancer cells and U937 leukemia cells
  di: Kedei, Noemi, et al.
  Pubblicazione: (2011)