Replacement of the Bryostatin A- and B-Pyran Rings With Phenyl Rings Leads to Loss of High Affinity Binding With PKC

Gelijkaardige items

• Synthesis of a des-B-Ring Bryostatin Analogue Leads to an Unexpected Ring Expansion of the Bryolactone Core
  door: Kraft, Matthew B., et al.
  Gepubliceerd in: (2014)
• Convergent Assembly of Highly Potent Analogues of Bryostatin 1 via Pyran Annulation: Bryostatin Look-alikes that Mimic Phorbol Ester Function
  door: Keck, Gary E., et al.
  Gepubliceerd in: (2008)
• The Bryostatin 1 A-Ring Acetate is Not the Critical Determinant for Antagonism of Phorbol Ester-Induced Biological Responses
  door: Keck, Gary E., et al.
  Gepubliceerd in: (2009)
• Synthetic Studies on the Bryostatins: Preparation of a Truncated BC-Ring Intermediate by Pyran Annulation
  door: Keck, Gary E., et al.
  Gepubliceerd in: (2005)
• Substitution on the A-Ring Confers to Bryopyran Analogues the Unique Biological Activity Characteristic of Bryostatins and Distinct From That of the Phorbol Esters
  door: Keck, Gary E., et al.
  Gepubliceerd in: (2009)