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Synthetic Studies Toward Bryostatin 1: Preparation of a C(1)-C(16) Fragment by Pyran Annulation

An expeditious assembly of a C(1)-C(16) subunit of bryostatin 1 is described. A pyran annulation reaction was utilized to form the B-ring by reaction of a hydroxy-allylsilane with a fully elaborated A-ring subunit. This annulation process proceeded with complete diastereoselectivity and in excellent...

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Hlavní autoři: Keck, Gary E., Welch, Dennie S., Poudel, Yam B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847416/
https://ncbi.nlm.nih.gov/pubmed/17404602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2006.09.094
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