BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia

[Image: see text] The therapeutic treatment of negative symptoms and cognitive dysfunction associated with schizophrenia is a significant unmet medical need. Preclinical literature indicates that α7 neuronal nicotinic acetylcholine (nACh) receptor agonists may provide an effective approach to treati...

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Udgivet i:ACS Med Chem Lett
Main Authors: King, Dalton, Iwuagwu, Christiana, Cook, Jim, McDonald, Ivar M., Mate, Robert, Zusi, F. Christopher, Hill, Matthew D., Fang, Haiquan, Zhao, Rulin, Wang, Bei, Easton, Amy E., Miller, Regina, Post-Munson, Debra, Knox, Ronald J., Gallagher, Lizbeth, Westphal, Ryan, Molski, Thaddeus, Fan, Jingsong, Clarke, Wendy, Benitex, Yulia, Lentz, Kimberley A., Denton, Rex, Morgan, Daniel, Zaczek, Robert, Lodge, Nicholas J., Bristow, Linda J., Macor, John E., Olson, Richard E.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2017
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346989/
https://ncbi.nlm.nih.gov/pubmed/28337332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00032
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