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Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs

Nicotinic acetylcholine receptors (nAChRs) are targets for developing new drugs to treat severe pain, nicotine addiction, Alzheimer disease, epilepsy, etc. α-Conotoxins are biologically and chemically diverse. With 12–19 residues and two disulfides, they can be specifically selected for different nA...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Lin, Bo, Xiang, Shihua, Li, Mengsen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082321/
https://ncbi.nlm.nih.gov/pubmed/27727162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14100173
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