From crystal structure of α-conotoxin GIC in complex with Ac-AChBP to molecular determinants of its high selectivity for α3β2 nAChR

Acetylcholine binding proteins (AChBPs) are unique spatial homologs of the ligand-binding domains of nicotinic acetylcholine receptors (nAChRs), and they reproduce some pharmacological properties of nAChRs. X-ray crystal structures of AСhBP in complex with α-conotoxins provide important insights int...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Lin, Bo, Xu, Manyu, Zhu, Xiaopeng, Wu, Yong, Liu, Xi, Zhangsun, Dongting, Hu, Yuanyan, Xiang, Shi-Hua, Kasheverov, Igor E., Tsetlin, Victor I., Wang, Xinquan, Luo, Sulan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772116/
https://ncbi.nlm.nih.gov/pubmed/26925840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22349
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk