Structural determinants of selective α-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP

The nicotinic acetylcholine receptor (nAChR) is the prototype member of the superfamily of pentameric ligand-gated ion channels. How the extracellular ligand-binding domain coordinates selective binding of ligand molecules to different subtypes of the receptor is unknown at the structural level. Her...

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Detaylı Bibliyografya
Asıl Yazarlar: Ulens, Chris, Hogg, Ronald C., Celie, Patrick H., Bertrand, Daniel, Tsetlin, Victor, Smit, August B., Sixma, Titia K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2006
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450132/
https://ncbi.nlm.nih.gov/pubmed/16505382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507889103
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