AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity

Neuronal nAChRs are a diverse family of pentameric ion channels with wide distribution throughout cells of the nervous and immune systems. However, the role of specific subtypes in normal and pathological states remains poorly understood due to the lack of selective probes. Here, we used a binding a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dutertre, Sébastien, Ulens, Chris, Büttner, Regina, Fish, Alexander, van Elk, René, Kendel, Yvonne, Hopping, Gene, Alewood, Paul F, Schroeder, Christina, Nicke, Annette, Smit, August B, Sixma, Titia K, Lewis, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952216/
https://ncbi.nlm.nih.gov/pubmed/17660751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601785
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados