Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease

Por Ito, Kazuhiro, Colley, Thomas, Mercado, Nicolas
Publicado em 2012

Inflammation to Pulmonary Diseases

Por Lee, Kang-Yun, Ito, Kazuhiro, Maneechotesuwan, Kittipong
Publicado no Mediators Inflamm (2016)

Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12

Por Ito, Kazuhiro, Barnes, Peter J., Adcock, Ian M.
Publicado em 2000

Nortriptyline Reverses Corticosteroid Insensitivity by Inhibition of Phosphoinositide-3-Kinase-δ

Por Mercado, Nicolas, To, Yasuo, Ito, Kazuhiro, Barnes, Peter J.
Publicado em 2011

Defects of Protein Phosphatase 2A Causes Corticosteroid Insensitivity in Severe Asthma

Por Kobayashi, Yoshiki, Mercado, Nicolas, Barnes, Peter J., Ito, Kazuhiro
Publicado em 2011

Epigenetics and airways disease

Por Adcock, Ian M, Ford, Paul, Ito, Kazuhiro, Barnes, P J
Publicado em 2006

Potent anti-inflammatory effects of the narrow spectrum kinase inhibitor RV1088 on rheumatoid arthritis synovial membrane cells

Por To, Wing S, Aungier, Susan R, Cartwright, Alison J, Ito, Kazuhiro, Midwood, Kim S
Publicado no Br J Pharmacol (2015)

Restoration of Corticosteroid Sensitivity in Chronic Obstructive Pulmonary Disease by Inhibition of Mammalian Target of Rapamycin

Por Mitani, Akihisa, Ito, Kazuhiro, Vuppusetty, Chaitanya, Barnes, Peter J., Mercado, Nicolas
Publicado no Am J Respir Crit Care Med (2016)

New drugs targeting Th2 lymphocytes in asthma

Por Caramori, Gaetano, Groneberg, David, Ito, Kazuhiro, Casolari, Paolo, Adcock, Ian M, Papi, Alberto
Publicado em 2008

Differential patterns of histone acetylation in inflammatory bowel diseases

Por Tsaprouni, Loukia G, Ito, Kazuhiro, Powell, Jonathan J, Adcock, Ian M, Punchard, Neville
Publicado em 2011

p38 Mitogen-Activated Protein Kinase-γ Inhibition by Long-Acting β(2) Adrenergic Agonists Reversed Steroid Insensitivity in Severe Asthma

Por Mercado, Nicholas, To, Yasuo, Kobayashi, Yoshiki, Adcock, Ian M., Barnes, Peter J., Ito, Kazuhiro
Publicado em 2011

Defect of Adaptation to Hypoxia in Patients With COPD Due to Reduction of Histone Deacetylase 7

Por To, Masako, Yamamura, Satoshi, Akashi, Kenichi, Charron, Catherine E., Barnes, Peter J., Ito, Kazuhiro
Publicado em 2012

The influence of severe hypoalbuminemia on the half-life of vancomycin in elderly patients with methicillin-resistant Staphylococcus aureus hospital-acquired pneumonia

Por Mizuno, Tomohiro, Mizokami, Fumihiro, Fukami, Kazuhiro, Ito, Kazuhiro, Shibasaki, Masataka, Nagamatsu, Tadashi, Furuta, Katsunori
Publicado em 2013

Reduced Denitration Activity in Peripheral Lung of Chronic Obstructive Pulmonary Disease

Por Osoata, Grace O., Ito, Misako, Elliot, Mark, Hogg, James, Barnes, Peter J., Ito, Kazuhiro
Publicado em 2012

Secondary electron emission and glow discharge properties of 12CaO·7Al(2)O(3) electride for fluorescent lamp applications

Por Watanabe, Satoru, Watanabe, Toshinari, Ito, Kazuhiro, Miyakawa, Naomichi, Ito, Setsuro, Hosono, Hideo, Mikoshiba, Shigeo
Publicado no Sci Technol Adv Mater (2011)

Theophylline Restores Histone Deacetylase Activity and Steroid Responses in COPD Macrophages

Por Cosio, Borja G., Tsaprouni, Loukia, Ito, Kazuhiro, Jazrawi, Elen, Adcock, Ian M., Barnes, Peter J.
Publicado em 2004

Suppression of GATA-3 Nuclear Import and Phosphorylation: A Novel Mechanism of Corticosteroid Action in Allergic Disease

Por Maneechotesuwan, Kittipong, Yao, Xin, Ito, Kazuhiro, Jazrawi, Elen, Usmani, Omar S., Adcock, Ian M., Barnes, Peter J.
Publicado em 2009

Improvements in thoracic surgery outcomes: a multi-institutional collaboration study

Por Iwasaki, Yasushi, Shimada, Junichi, Kato, Daishiro, Nishimura, Motohiro, Ito, Kazuhiro, Terauchi, Kunihiko, Shimomura, Masanori, Tsunezuka, Hiroaki
Publicado no J Cardiothorac Surg (2015)

Protein tyrosine phosphatase PTP-RR regulates corticosteroid sensitivity

Por Kobayashi, Yoshiki, Ito, Kazuhiro, Kanda, Akira, Tomoda, Koich, Miller-Larsson, Anna, Barnes, Peter J., Mercado, Nicolas
Publicado no Respir Res (2016)

A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression

Por Ito, Kazuhiro, Lim, Sam, Caramori, Gaetano, Cosio, Borja, Chung, K. Fan, Adcock, Ian M., Barnes, Peter J.
Publicado em 2002