How Variability in Clinical Phenotypes Should Guide Research into Disease Mechanisms in Asthma

Por Chung, Kian Fan, Adcock, Ian M.
Publicado em 2013

Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12

Por Ito, Kazuhiro, Barnes, Peter J., Adcock, Ian M.
Publicado em 2000

Profile of fluticasone furoate/vilanterol dry powder inhaler combination therapy as a potential treatment for COPD

Por Caramori, Gaetano, Chung, Kian Fan, Adcock, Ian M
Publicado em 2014

A novel transcription factor inhibitor, SP100030, inhibits cytokine gene expression, but not airway eosinophilia or hyperresponsiveness in sensitized and allergen-exposed rat

Por Huang, Tung-Jung, Adcock, Ian M, Chung, K Fan
Publicado em 2001

Epigenetics and airways disease

Por Adcock, Ian M, Ford, Paul, Ito, Kazuhiro, Barnes, P J
Publicado em 2006

Simvastatin Suppresses Airway IL-17 and Upregulates IL-10 in Patients With Stable COPD

Por Maneechotesuwan, Kittipong, Wongkajornsilp, Adisak, Adcock, Ian M., Barnes, Peter J.
Publicado no Chest (2015)

Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-κB and lack of I-κB involvement

Por Adcock, Ian M, Nasuhara, Yasuyuki, Stevens, David A, Barnes, Peter J
Publicado em 1999

Modulation of LPS stimulated NF-kappaB mediated Nitric Oxide production by PKCε and JAK2 in RAW macrophages

Por Jones, Edward, Adcock, Ian M, Ahmed, Bushra Y, Punchard, Neville A
Publicado em 2007

Brd4 Is Essential for IL-1β-Induced Inflammation in Human Airway Epithelial Cells

Por Khan, Younis M., Kirkham, Paul, Barnes, Peter J., Adcock, Ian M.
Publicado em 2014

Cytokine inhibition in the treatment of COPD

Por Caramori, Gaetano, Adcock, Ian M, Di Stefano, Antonino, Chung, Kian Fan
Publicado em 2014

Epigenetics and Chromatin Remodeling Play a Role in Lung Disease

Por Mortaz, Esmaeil, Masjedi, Mohammad Reza, Barnes, Peter J, Adcock, Ian M
Publicado em 2011

Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung disease

Por Durham, Andrew L., Caramori, Gaetano, Chung, Kian F., Adcock, Ian M.
Publicado no Transl Res (2016)

Role of P2X7 Receptors in Release of IL-1β: A Possible Mediator of Pulmonary Inflammation

Por Mortaz, Esmaeil, Adcock, Ian M, Shafei, Hamed, Masjedi, Mohammad Reza, Folkerts, Gert
Publicado em 2012

Epigenome-modifying tools in asthma

Por Brook, Peter O, Perry, Mark M, Adcock, Ian M, Durham, Andrew L
Publicado no Epigenomics (2015)

New drugs targeting Th2 lymphocytes in asthma

Por Caramori, Gaetano, Groneberg, David, Ito, Kazuhiro, Casolari, Paolo, Adcock, Ian M, Papi, Alberto
Publicado em 2008

Differential patterns of histone acetylation in inflammatory bowel diseases

Por Tsaprouni, Loukia G, Ito, Kazuhiro, Powell, Jonathan J, Adcock, Ian M, Punchard, Neville
Publicado em 2011

p38 Mitogen-Activated Protein Kinase-γ Inhibition by Long-Acting β(2) Adrenergic Agonists Reversed Steroid Insensitivity in Severe Asthma

Por Mercado, Nicholas, To, Yasuo, Kobayashi, Yoshiki, Adcock, Ian M., Barnes, Peter J., Ito, Kazuhiro
Publicado em 2011

Immunological Features of Chronic Obstructive Pulmonary Disease (COPD) Induced by Indoor Pollution and Cigarette Smoke

Por Mortaz, Esmaeil, Barnes, Peter J., Heidarnazhad, Hassan, Adcock, Ian M., Masjedi, Mohammad Reza
Publicado em 2012

Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function

Por Marwick, John A, Stevenson, Christopher S, Chung, Kian Fan, Adcock, Ian M, Kirkham, Paul A
Publicado em 2010

Airway Smooth Muscle Hyperproliferation Is Regulated by MicroRNA-221 in Severe Asthma

Por Perry, Mark M., Baker, Josie E., Gibeon, David S., Adcock, Ian M., Chung, Kian Fan
Publicado em 2014