Role of P2X7 Receptors in Release of IL-1β: A Possible Mediator of Pulmonary Inflammation

Extracellular ATP is a signaling molecule which plays an important role in alerting the immune system in case of any tissue damage. Recent studies show that binding of ATP to the ionotropic P2X7 receptor of inflammatory cells (macrophages and monocytes) will induce caspase 1 activation. Stimulation...

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Autors principals: Mortaz, Esmaeil, Adcock, Ian M, Shafei, Hamed, Masjedi, Mohammad Reza, Folkerts, Gert
Format: Artigo
Idioma:Inglês
Publicat: National Research Institute of Tuberculosis and Lung Disease 2012
Matèries:
Review Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153200/
https://ncbi.nlm.nih.gov/pubmed/25191407
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