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Role of P2X7 Receptors in Release of IL-1β: A Possible Mediator of Pulmonary Inflammation
Extracellular ATP is a signaling molecule which plays an important role in alerting the immune system in case of any tissue damage. Recent studies show that binding of ATP to the ionotropic P2X7 receptor of inflammatory cells (macrophages and monocytes) will induce caspase 1 activation. Stimulation...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Research Institute of Tuberculosis and Lung Disease
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153200/ https://ncbi.nlm.nih.gov/pubmed/25191407 |
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