Učitavanje...
Theophylline Restores Histone Deacetylase Activity and Steroid Responses in COPD Macrophages
Chronic obstructive pulmonary disease (COPD) is a common chronic inflammatory disease of the lungs with little or no response to glucocorticoids and a high level of oxidative stress. Histone deacetylase (HDAC) activity is reduced in cells of cigarette smokers, and low concentrations of theophylline...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2004
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212744/ https://ncbi.nlm.nih.gov/pubmed/15337792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040416 |
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